Q: Can I stuff the Thanksgiving turkey the night before baking?
A: You should never stuff a bird hours before roasting, as the cavity can provide an environment for bacteria to grow. When cooking stuffing in a turkey, it is always best to prepare it just before filling and roasting the bird. The stuffing should be warm when placed in the turkey so it cooks and reaches 160 degrees F (70 degrees C) by the time the turkey is done. Stuffing should always reach a temperature of at least 160 degrees F (70 degrees C) to kill bacteria. This temperature can be measured by placing a meat thermometer into the center of the body cavity. If the turkey is finished cooking before the stuffing has reached the correct temperature scoop it out, and place it in a greased baking dish. Microwave it on high or bake it at 350 degrees F (175 degrees C) until it reaches 160 degrees F (70 degrees C).
…More on Choosing the right Stuffing
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